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Dutch pathologist-anatomist, who described the type 2 glycogen storage disease Morbus Pompe. He was the youngest child of the Catholic Cornelis Andreas Pompe (15 March 1874, Utrecht - 22 Oct 1944, Maartensdijk) and Johanna Maria Alijda Brom (1874- 28 March 1905, Utrecht). They married 24 November 1891 in Utrecht and got between 1993 and 1901 twelve children. After Maria's death his father remarried on 27 September 1911 her sister Arnolda Catharina Maria Brom (1862 - 21 November 1925, Utrecht). Pompe studied medicine at the University of Amsterdam. On 27 December 1930 he did autopsy of a 7 months old child with an enlarged heart and also noted enlargement of other body organs. The girl was a patient of Prof. Isidore Snapper (5 January 1889 1 PM, Amsterdam - 30 June 1973, New York) , who also had published on Von Gierke disease, now known as glycogen storage disease type 1. He discussed the unknown disease on 18 November 1931 with other physicians in Amsterdam. Today Pompe's disease is known as an autosomal recessive metabolic disorder, characterized by storage of glycogen in organs and tissues, and associated with deficiency of the lysosomal enzyme acid maltase or alpha-1,4 glucosidase. As the glycogen cannot be metabolised, it accumulates in the tissues. He dissertated on 11 August 1936 with "Cardiomegalia glycogenica" In Nijmegen. After a spell at the St. Canisius Hospital in Nijmegen, he was appointed as Pathologist at Onze Lieve Vrouwen Gasthuis (OLVG, Our Loved Woman Guesthouse) in Amsterdam, where he worked from June 1939 until his death. When the Germans invaded the Netherlands, Pompe was called to arms. During the war he became active in resistance. He kept persecuted people in his laboratory and there was also an illegal transmitter in the animal house to contact the UK. Tre location of the transmitter was detected by the Germans. On Sunday 25 February 1945, at 10 am, 40-50 members of the SD entered the hospital. The wireless operator, Pierre Antoine Coronel (26 December 1914, Ouder-Amstel - 25 February 1945, Amsterdam), was broadcasting at the time and tried to resist. He was executed in the courtyard of the hospital. Pompe was warned and decided to hide, but was caught before he could leave. On April 14, 1945, the resistance blew up a railway bridge near St Pancras, destroying an army train in the process. As a reprisal, 20 Dutch prisoners, including Pompe and the animal keeper Louis Andreas Berben (26 Jan 1903, Amsterdam - 15 April 1945, Sint Pancras) were shot the next day at around 9 PM. The bodies were buried in a mass grave in dunes of Overveen. Personal On 1 October 1930 he married Augusta Maria Constantia Stordiau (1912, Antwerpen) in Amsterdam. Pompe was described as a Catholic polymath - a man of both science and the arts. His brother Willem Petrus Joseph Pompe (10 Match 1893 2 AM, Utrecht - 26 july 1968, Utrecht) became a noted criminologist. Link to Wikipedia
S.No. | Event Type | Event Date | Event Description |
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1 |
Begin Major Project |
Dec. 27, 1930 |
Work : Begin Major Project 27 December 1930 in Amsterdam (autopsy of a 7 months old child with Pompe's disease) . |
2 |
Published/Released |
Nov. 18, 1931 |
Work : Published/ Exhibited/ Released 18 November 1931 (Pompe en zijn ziekte) . |
3 |
Published/Released |
May 15, 1936 |
Work : Published/ Exhibited/ Released 15 May 1936 at 4:30 PM in Nijmegen (Thesis Cardiomegalia glycogenica) . |
S.No. | Event Type | Event Date | Event Description |
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1 |
Marriage |
Oct. 1, 1930 |
Relationship : Marriage 1 October 1930 in Amsterdam (Augusta Maria Constantia Stordiau) . |
S.No. | Event Type | Event Date | Event Description |
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1 |
Mother Death |
March 28, 1905 |
Death of Mother 28 March 1905 in Utrecht (Johanna Maria Alijda Brom) . |
2 |
Signficant Person Death |
Nov. 21, 1925 |
Death of Significant person 21 November 1925 in Utrecht (Aunt and stepmother: Arnolda Catharina Maria Brom) . |
3 |
Father Death |
Oct. 22, 1944 |
Death of Father 22 October 1944 in Maartensdijk (Cornelis Andreas Pompe, born 15 March 1874, Utrecht) . |
4 |
Execution |
April 15, 1945 |
Death by Execution 15 April 1945 at 9:00 PM in Sint Pancras . |
S.No. | Event Type | Event Date | Event Description |
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1 |
Arrested |
Feb. 25, 1945 |
Crime : Arrest 25 February 1945 in Amsterdam . |
S.No. | Event Type | Event Date | Event Description |
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1 |
Other Misc. |
Nov. 1, 1979 |
Other Misc. 7 November 1979 at 3:00 PM in Rotterdam (Thesis: The viability of Pompe's disease by Maria Chistina Bernadette Loonen) . |
Gender | Male |
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Weekday | Monday |
Date | Sept. 9, 1901 |
Time | 11 a.m. |
Daylight Saving | No |
City | Utrecht, Utrecht, Netherlands |
Geo-location | 52ºN5'26.99", |
Timezone | Europe/Amsterdam |
City | Utrecht, Utrecht, Netherlands |
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Timezone | Europe/Amsterdam |
Time (Europe/Amsterdam) | Sep. 09, 1901, 10:57:58 AM |
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Time (UTC) | Sep. 09, 1901, 10:40:28 AM |
Time (LMT) | Sep. 09, 1901, 11:00:57 AM |
Time (Julian) | 2415636.94476852 |
LMT Correction | 0.3414 Hrs |
Ayanmsha | True Chitra - 22º27'53.74" |